Membranous Glomerulonephritis with ANCA-Associated Necrotizing and Crescentic Glomerulonephritis

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Membranous glomerulonephritis with ANCA-associated necrotizing and crescentic glomerulonephritis.

BACKGROUND AND OBJECTIVES Only rare cases of concurrent membranous glomerulonephritis (MGN) and antineutrophil cytoplasmic antibody (ANCA)-associated necrotizing and crescentic glomerulonephritis (NCGN) have been reported. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The authors report the clinical and pathologic findings in 14 patients with MGN and ANCA-associated NCGN. RESULTS The cohort...

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Membranous glomerulopathy with superimposed pauci-immune necrotizing crescentic glomerulonephritis

We describe a 61-year-old woman with acute kidney injury, nephrotic range proteinuria and hematuria. Kidney biopsy showed membranous glomerulopathy (MG) with superimposed pauci-immune necrotizing crescentic glomerulonephritis (PNCGN). Coexistent MG and PNCGN is a rare occurrence. The diagnosis of such an exceptionally rare combination relies on the combination of renal biopsy findings and serol...

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Infective endocarditis mimics ANCA associated glomerulonephritis

Background: Sub-acute bacterial endocarditis (SBE) rarely presents with features of a small vessel vasculitis. Patients with SBE can also develop multiple serological abnormalities including ANCA. In this report, we present a case of infective endocarditis mimicked ANCA associated glomerulonephritis.Case presentation: A 57-year old male with a clinical picture of rapidly progressive renal failu...

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Coexistent Membranous Nephropathy with Doubly ANCA-Associated Crescentic Glomerulonephritis: A Case Report and Review of Literature

Introduction: Membranous nephropathy (MN) is the most common causes of the nephrotic syndrome in nondiabetic, Caucasian adults. Pauci-immune necrotizing and crescentic glomerulonephritis (PNCGN) typically present with rapidly progressive glomerulonephritis. Coexistent MN and PNCGN is a rare occurrence. We report a case of both MPOand PR3-ANCA associated NCGN with MN that presented as rapidly pr...

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MPO-C-ANCA-associated necrotising and crescentic glomerulonephritis

The patterns of ANCA staining usually relate closely to antibodies against myeloperoxidase and proteinase-3. C-ANCA is mainly antibodies to proteinase-3 and P-ANCA is antibodies to myeloperoxidase. C-ANCA with antibodies to MPO with clinical sequelae is unusual.

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ژورنال

عنوان ژورنال: Clinical Journal of the American Society of Nephrology

سال: 2009

ISSN: 1555-9041,1555-905X

DOI: 10.2215/cjn.04060808